Advancing Investigational
Photo Neuromodulation for Parkinson’s Disease

Celeste® is an investigational device being studied to better understand the role of
retinal and circadian signaling pathways in Parkinson’s disease. 

Addressing Major Unmet Needs
in Parkinson’s Disease

Parkinson’s disease affects more than 11 million people worldwide, a number expected to grow significantly in the coming decades. While advances in symptom management have helped many people live longer and more active lives, substantial unmet needs remain.

Many individuals living with Parkinson’s disease experience challenges that extend beyond movement, including sleep disturbances, fatigue, mood changes, cognitive difficulties, and disruptions to daily life. These symptoms can significantly impact independence, wellbeing, and overall quality of life.

PhotoPharmics was founded to explore whether targeted light-based interventions may influence biological pathways involved in neurological function. The company’s research focuses on the relationship between light-responsive retinal pathways, circadian biology, and the brain.

Celeste® is an investigational photo-neuromodulation device being evaluated for Parkinson’s disease. Through a series of clinical studies, PhotoPharmics has explored the potential role of this approach in addressing important unmet needs within the Parkinson’s community.

We are grateful to the participants, caregivers, investigators, researchers, and advocates who have contributed to this work and invite you to follow our ongoing scientific and regulatory journey.

Light for PD Trial Completed

Receive updates regarding the Celeste® clinical and regulatory program

Seeing Photo-Neuromodulation Clearly

Celeste® is an investigational photo-neuromodulation device being evaluated for Parkinson’s disease.

SCIENCE-BASED

Built upon research exploring how light-responsive retinal pathways communicate with broader neurological systems.

NON-INVASIVE

Designed to deliver light through the eyes
without surgery or implanted hardware.

HOME-BASED

Developed for use in a familiar home environment
as part of ongoing clinical research.

Exploring New Approaches
to Neurodegenerative Disease

Our initial clinical focus is Parkinson’s disease.
Additional applications may be evaluated
through future research programs.

LATEST UPDATES

Understanding Parkinson’s Fatigue

Understanding Parkinson’s Fatigue

Introduction Imagine waking up after a full night’s sleep, yet feeling as though you haven’t slept in days. Your limbs feel heavy, as if you are moving through molasses, and the mental effort required to simply plan your day feels akin to solving complex calculus. ...

The Role of Nutrition in Parkinson’s Disease

The Role of Nutrition in Parkinson’s Disease

Introduction Did you know that unintentional weight loss and nutritional deficiencies are among the most common challenges for people with Parkinson’s disease, often occurring even before a diagnosis is made? In simple terms, Parkinson’s Disease is a condition where...